Although ALA treatment caused a slight weight loss, it was not statistically significant. Appetite scores were decreased in the diabetes group but it did not cause statistically significant weight loss. There was no significant change in metabolic parameters or adiponectin after the treatment.
Is alpha-lipoic acid good for autoimmune disease?
Studies also show that ALA is beneficial in certain autoimmune diseases, including rheumatoid arthritis (RA) and multiple sclerosis (MS).
What is alpha-lipoic acid used to treat?
People most commonly use alpha-lipoic acid for nerve pain in people with diabetes. It is also used for obesity, altitude sickness, aging skin, high levels of cholesterol or other fats in the blood, and many other purposes, but there is no good scientific evidence to support many of these other uses.
Does alpha-lipoic acid help with insulin resistance?
We have strong evidence that alpha-lipoic acid supplements help with type 2 diabetes. Several studies have found that they can improve insulin resistance. Studies also found that alpha-lipoic acid supplements can help with neuropathy — nerve damage — caused by diabetes or cancer treatment.
Is alpha lipoic good for weight loss?
However, human studies show that alpha-lipoic acid only slightly impacts weight loss. An analysis of 12 studies discovered that people who took an alpha-lipoic acid supplement lost an average of 1.52 pounds (0.69 kg) more than those taking a placebo over an average of 14 weeks ( 8 ).
Can alpha-lipoic acid cause low blood sugar?
Because ALA could possibly lower blood sugar levels, you might also have symptoms of hypoglycemia (weakness, lightheadedness, headache, sweating, confusion, irritability, fast heart rate) if you take ALA and also take insulin or diabetes pills that can cause low blood sugar.
What is the best time to take lipoic acid?
Alpha-lipoic supplements are best taken on an empty stomach, as certain foods can lower the acid’s bioavailability (40). Though there is no set dosage, most evidence suggests that 300–600 mg is sufficient and safe.
Can alpha-lipoic acid be taken with vitamin C?
No interactions were found between alpha-lipoic acid and Vitamin C. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
What is the best supplement for insulin resistance?
Many different supplements may increase insulin sensitivity, but chromium, berberine, magnesium, and resveratrol are backed by the most consistent evidence. Chromium is a mineral involved in carb and fat metabolism.
How does alpha lipoic acid reduce blood sugar?
What is alpha-lipoic acid? Made naturally in the body and found in every cell, alpha lipoic acid is an antioxidant that helps turn glucose into energy. Unlike other antioxidants, it is both fat- and water-soluble, which means it can work anywhere in the body.
Does alpha-lipoic acid make you gain weight?
In animal studies, it has showed that ALA supplementation promotes the reduction of body weight and fat mass by decreasing food intake and enhancing energy expenditure, possibly by suppressing hypothalamic AMP-activated protein kinase (AMPK) activity (19-22).
