UniProt uses InterPro to classify sequences at superfamily, family and subfamily levels and to predict the occurrence of functional domains and important sites. InterPro matches are automatically annotated to UniProtKB entries as database cross-references with every InterPro release.
What does ovalbumin mean?
Definition of ovalbumin 1 : the principal albumin of white of egg especially : the crystalline part of egg albumins. 2 : dried whites of eggs.
Is ovalbumin a structural protein?
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up approximately 55% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor….
| Ovalbumin | |
|---|---|
| UniProt | P01012 |
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What are the features of Uniprot?
THE UNIPROT KNOWLEDGEBASE (UNIPROT)
- High-quality annotation.
- Manual annotation by curators based on literature and sequence analysis.
- Automatic classification and annotation.
- High-quality Automated and Manual Annotation of microbial Proteomes (HAMAP)
- Standardized nomenclature and controlled vocabularies.
Is Uniprot manually curated?
In order to respond to the flood of sequencing data, UniProt provides both manual curation and automatic annotation.
Why is ovalbumin very important?
Ovalbumin is the first protein isolated in pure form and is about half of the total egg albumen protein. It is best known for its various biological activities, like anticancer, antihypertensive, antimicrobial, antioxidant, and immune-modulating activities.
Is ovalbumin the same as albumin?
Other albumin types A few other proteins are also sometimes called albumins. They are not in the same family as vertebrate albumins: Ovalbumin is a storage protein in egg white (albumen). It is a serpin.
Why is ovalbumin used in vaccines?
Ovalbumin (OVA) is a key reference protein for vaccination experiments. Ovalbumin, the major protein constituent of chicken egg whites, is a glycoprotein that is sufficiently large and complex to be mildly immunogenic. Consequently, it is widely used as an antigen for immunization research.
What is ovalbumin made of?
Ovalbumin has a molecular mass of 45 kDa and is composed of 385 amino acids. This protein belongs to the serpins family and possesses two genetic variants which differ at residue 289 and 311 by a substitution of Glu and Asn, respectively, by Gln and Asp (Ishihara et al., 1981; Wiseman et al., 1972).
Is ovalbumin globular or fibrous?
Ovalbumin is an example of a globular protein, one that is water-soluble and shaped roughly like a globe or a sphere when coiled up into its functional form.
What kind of protein is ovalbumin?
egg white protein
Ovalbumin is the predominant protein in albumen and represents 54% to 58% of the egg white protein by weight. It is a monomeric phosphoglyco-protein with a molecular weight of 44.5 kDa and an isoelectric point (IEP) of 4.5.
